Which drug is an immune checkpoint inhibitor used in cancer therapy?

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Multiple Choice

Which drug is an immune checkpoint inhibitor used in cancer therapy?

Explanation:
Immune checkpoint inhibitors unleash T cells to attack cancer by blocking inhibitory signals that normally restrain the immune response. Pembrolizumab is a monoclonal antibody that targets the PD-1 receptor on T cells, preventing PD-L1/PD-L2 from turning off T cells and thus boosting anti-tumor activity. The other drugs have different roles: bevacizumab blocks VEGF to hinder tumor blood vessel growth; doxorubicin is a cytotoxic chemotherapy that damages DNA in rapidly dividing cells; amifostine protects normal tissues from radiation or chemotherapy toxicity. So pembrolizumab is the immune checkpoint inhibitor among these options.

Immune checkpoint inhibitors unleash T cells to attack cancer by blocking inhibitory signals that normally restrain the immune response. Pembrolizumab is a monoclonal antibody that targets the PD-1 receptor on T cells, preventing PD-L1/PD-L2 from turning off T cells and thus boosting anti-tumor activity. The other drugs have different roles: bevacizumab blocks VEGF to hinder tumor blood vessel growth; doxorubicin is a cytotoxic chemotherapy that damages DNA in rapidly dividing cells; amifostine protects normal tissues from radiation or chemotherapy toxicity. So pembrolizumab is the immune checkpoint inhibitor among these options.

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