VEGF inhibitors primarily aim to:

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Multiple Choice

VEGF inhibitors primarily aim to:

Explanation:
VEGF inhibitors target the signal that tells blood vessels to grow toward tumors. Tumors often secrete VEGF to recruit new vessels to supply oxygen and nutrients. By blocking VEGF signaling—either trapping the VEGF ligand or inhibiting its receptor on endothelial cells—the growth of new vasculature is suppressed. This reduces the tumor’s blood supply, slowing growth, and can even help normalize abnormal vessels, which may improve delivery of other therapies. This main action is distinct from strategies that energize the immune system (like PD-1 blockade) or from drugs that kill cancer cells directly by alkylating their DNA.

VEGF inhibitors target the signal that tells blood vessels to grow toward tumors. Tumors often secrete VEGF to recruit new vessels to supply oxygen and nutrients. By blocking VEGF signaling—either trapping the VEGF ligand or inhibiting its receptor on endothelial cells—the growth of new vasculature is suppressed. This reduces the tumor’s blood supply, slowing growth, and can even help normalize abnormal vessels, which may improve delivery of other therapies. This main action is distinct from strategies that energize the immune system (like PD-1 blockade) or from drugs that kill cancer cells directly by alkylating their DNA.

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